Alex Scott
Assistant Professor, Department of Physical Therapy
PhD
Contact Information
Office location
772-2635 Laurel Street
Robert H.N. Ho Research Centre
Vancouver, BC, V5Z 1M9
Lab location
Centre for Hip Health and Mobility
2635 Laurel Street
Robert H.N. Ho Research Centre
Vancouver, BC V5Z 1M9
Phone
604 875 4111 x21810 (Lab)
More Info
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Dr. Scott's teaching interests include the principles of mechanobiology and tissue healing-core concepts for the Physiotherapy profession. He encourages students to think biologically, and to maintain a questioning and open approach to traditional and emerging treatments. Building students' confidence in the concepts of mechanobiology and tissue pathology will empower them, as clinicians, to advocate for an active rehabilitation approach with patients and colleagues.
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Dr. Scott's teaching interests include the principles of mechanobiology and tissue healing-core concepts for the Physiotherapy profession. He encourages students to think biologically, and to maintain a questioning and open approach to traditional and emerging treatments. Building students' confidence in the concepts of mechanobiology and tissue pathology will empower them, as clinicians, to advocate for an active rehabilitation approach with patients and colleagues.
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Affiliation and Links
- Hosting the Second International Scientific Tendinopathy Symposium
- Experimental Medicine Program
- Biomedical Research Centre
- Centre for Hip Health and Mobility
- Michael Smith Foundation for Health Research (Scholar)
Service
- Physiotherapy Association of BC (lectures, research reports, knowledge translation initiatives)
- Physiotherapy Foundation of Canada, grant reviewer
- Editorial Board Member, BJSM, 2007-present
- Journal reviewer, British Medical Journal and others
- Canadian Physiotherapy Association, scholarship review panel
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Dr. Scott is a graduate of the UBC Physical Therapy program, and the UBC Experimental Medicine PhD program. His research targets a widespread problem, overuse injuries and chronically painful tendon disorder in workers and athletes. His research has been highlighted and supported locally by organizations including the WorksafeBC, Professional Association of BC and the Health Sciences Association, nationally through CIHR sponsored events and seminars, and internationally including sponsorship by the Canada-Scandinavia Foundation and the Swedish Research Council. He maintains active collaborations with Oslo University, Umeå University, and University of Paris. His work has been incorporated into widely used web-based clinical guidelines such as UpToDate©, and the Journal of Orthopaedic and Sports Physical Therapy clinical guideline on Achilles tendinopathy.
Research Page
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Dr. Scott is a graduate of the UBC Physical Therapy program, and the UBC Experimental Medicine PhD program. His research targets a widespread problem, overuse injuries and chronically painful tendon disorder in workers and athletes. His research has been highlighted and supported locally by organizations including the WorksafeBC, Professional Association of BC and the Health Sciences Association, nationally through CIHR sponsored events and seminars, and internationally including sponsorship by the Canada-Scandinavia Foundation and the Swedish Research Council. He maintains active collaborations with Oslo University, Umeå University, and University of Paris. His work has been incorporated into widely used web-based clinical guidelines such as UpToDate©, and the Journal of Orthopaedic and Sports Physical Therapy clinical guideline on Achilles tendinopathy.
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1. Mechanisms of rotator cuff injury. Kirsten Lundgreen, Lars Engebretsen, A Scott. Putting Research to Work. WorksafeBC, March 7-14, 2011.
2. Working towards new treatments for lateral epicondylalgia. Research round-table. WorksafeBC, Sep 23, 2011.
3. Laboratory models of tendinopathy. Institute of Sports Medicine, University of Copenhagen, Bispebjerg Hospital. May 25, 2011.
4. Tendinopathy: overuse or underuse injury? Physiotherapy Association of B.C. Rapid Research Forum, Annual General Meeting, April 3 2011.
5. What’s new in treatment of tendon conditions and why it works. WorksafeBC Medical Advisory Board. Dec 9, 2010. Also available to WorksafeBC medical advisors on DVD.
6. Role of mast cells in tendon extracellular remodeling. International tendinopathy symposium, Umea University, Sept 30 2010.
7. Tendon overuse pathophysiology – research update and clinical implications. University of Paris, Laboratoire CRRET – croissance, reparation et regeneration tissulaires. July 9 2010.
8. Andersson G, Backman L, Scott A, Lorentzon R, Forsgren S, and Danielson P. Substance P accelerates tendinosis-like changes in response to Achilles tendon overuse. British Journal of Sports Medicine. E-pub May 2, 2011.
9. M Attia, A Scott, LJ Soslowsky, A Duchesnay, T van Kuppevelt, G Carpentier, D Papy-Garcia, J Courty, M Tassoni, I Martelly. Alterations of overused supraspinatus tendon: a role of glycosaminoglycans and HARP/Pleiotrophin in early tendon pathology. J Orthop Res. 2011 E pub Jun 17.
10. K. Lundgreen, Ø. Lian, L. Engebretsen, A. Scott. Tenocyte apoptosis in the torn rotator cuff: a primary or secondary pathological event? British Journal of Sports Medicine, Br J Sports Med. 2011 E pub Apr 10.
11.Scott A, T Abraham, G Fong, A Sampaio, T Underhill. Mechanical force modulates scleraxis expression in bioartificial tendons. Journal of Musculoskeletal and Neuronal Interactions. J Musculoskelet Neuronal Interact 2011; 11(2):124-132.
12. T Abraham, G Fong, Scott A,. Second harmonic generation analysis of early tendinosis lesions. BMC Musculoskeletal Disorders, Vol. 12 (26 January 2011), 26.
13. Scott A, A Sampaio, T Abraham, C Duronio, TM Underhill. Scleraxis expression is coordinately regulated in a murine model of patellar tendon injury. Journal of Orthopaedic Research, 29(2):289-96 (2011). February
14. Sharma A, T Abraham, A Sampaio, M Cowan, TM Underhill, A Scott. Sodium cromolyn reduces expression of CTGF, ADAMTS1 and TIMP3 and modulates post-injury patellar tendon morphology. Journal of Orthopaedic Research E pub December 2010.
15. Spang C, A Scott, P Danielson, R Lorentzon, S Forsgren. VGluT2- and NMDAR1- expression in cells in the inflammatory infiltrates in experimentally induced myositis: Evidence of local glutamate signaling suggests autocrine/paracrine effects in an overuse injury model. Inflammation. Epub December 2010.
16. Andersson G, Forsgren S, Stjernfeldt JE, Lorentzon R, Scott A, Alfredson H, Backman C, Danielson P. Tenocyte hypercellularity and vascular proliferation confirm a rabbit model for tendinopathy – contralateral effects suggest the involvement of central neuronal mechanisms. British Journal of Sports Medicine. E pub July 2010.
17. Inter-adipose septa in bursa stroma may explain ultrasound reports of bursa thickening.19th Annual Meeting of the European Orthopaedic Research Society, September 1 - 2, 2011, Vienna, Austria. AM Fearon, J. Twin, JE Dahlstrom, JL Cook, W Cormick, A Scott, PN Smith.
18.Inter-adipose septa in bursa stroma may explain ultrasound reports of bursa thickening. 7th Congress of the European Federation of IASP Chapters (EFIC) - PAIN IN EUROPE VII Hamburg, Germany, September 21 - 24, 2011. AM Fearon, J. Twin, JE Dahlstrom, JL Cook, W Cormick, A Scott, PN Smith.
19. What is the best treatment for Achilles tendinopathy? Canadian Physiotherapy Association national congress, July 2011. E Huisman, A Scott.
20. Effect of rest insertion on collagen (col1a1) gene expression in response to mechanical loading: a laboratory study. A Sharma, P Danielson, K Silbernagl, A Scott. World Congress of Physical Therapy, Amsterdam June 2011.
21. Second Harmonic Generation Imaging of Collagen Matrix Remodeling in Stimulated 3D Cellular Environment: Forward vs Backward Scattering. Photonics West meeting, Jan 23 2011. T Abraham, A Scott, B MacManus.
22. Apoptosis in full-thickness tears of the supraspinatus tendon. International tendinopathy symposium, Umea University,.Sept 30 2010. K Lundgreen, A Scott, O Lian, L Engebretsen. International tendinopathy symposium, Umea University,.Sept 30 2010.
23.A biochemical model for tendinpoathy pathology – what is the role of non-neuronal signal substances in chronic tendon pain and structural tissue changes, and how do we test it? Backman L, Andersson G, Scott A, Danielson P. International tendinopathy symposium, Umea University,.Sept 30 2010.
24. Characterization of human Achilles tendon cells in respect to effects of Substance P stimulation in vitro. Fong G, Backman L, Scott A, Alfredson H, Oldenborg P-A, Danielson P. International tendinopathy symposium, Umea University,.Sept 30 2010
25. Is glutamate signaling of importance for the musculoskeletal system? Studies on myositis in response to muscle overuse and injections into the loose paratendinous tissue of the Achilles tendon. International tendinopathy symposium, Umea University,.Sept 30 2010. C Spang, A Scott, P Danielson, R Lorentzon, S Forsgren.
26. Hart DA, Scott A. Getting the dose right when prescribing exercise: the Ying and the Yang of tissue homeostasis. BJSM . September 2011.
27. Warden S, Scott A. JMNI special issue—Tendons: the connection between muscle and bone. Editorial, JMNI June 2011.
28. Danielson P, Scott A. Biochemical Causes of Patellar Tendinopathy. In: Anterior Knee Pain 2nd ed. Editor: Vicente Sanchis Alfonso; Spriger-Verlag, London July 2011
29. B Vicenzino, A Scott, S Bell. Elbow and arm pain. Clinical Sports Medicine, 4th ed. New York: McGraw Hill Co. In press.
30. Grävare-Silbernagel, P Malliaras, A Scott, J Karlsson. Noninvasive conservative management. Pathology at the Insertion of the Achilles Tendon. J. J. Wiegerinck. Guildford, UK., DJO Publications. In press.
See publications by A Scott on PubMed
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1. Mechanisms of rotator cuff injury. Kirsten Lundgreen, Lars Engebretsen, A Scott. Putting Research to Work. WorksafeBC, March 7-14, 2011.
